Jie Jia, Pengcheng Xun, Xinling Wang, Ka He, Qingya Tang, Tian Zhang ,Ying Wang, Wenjing Tang, Lina Lu, Weihui Yan, Weiping Wang, Tianyi Hu, Wei Cai*. Impact of Postnatal Antibiotics and Parenteral Nutrition on the Gut Microbiota in Preterm Infants During Early Life. JPEN J Parenter Enteral Nutr, 2020 May;44(4):639-654 |
Tian Zhang#, Yang Liu#, Jun-Kai Yan*, Wei Cai*. Early downregulation of P-glycoprotein facilitates bacterial attachment to intestinal epithelial cells and thereby triggers barrier dysfunction in a rodent model of total parenteral nutrition. FASEB Journal, 2020 Mar;34(3):4670-4683 |
Qiu Y, Sun S, Yu X, Zhou J, Cai W*, Qian L*. Carboxyl ester lipase is highly conserved in utilizing maternal supplied lipids during early development of zebrafish and human. Biochim Biophys Acta Mol Cell Biol Lipids, 2020 Feb 12;1865(6):158663 |
Yang Wang#, Qian Jiang#, Hao Cai, Ze Xu, Wenjie Wu, Beilin Gu, Long Li*, Wei Cai*. Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease. Aging, 2020 Mar 6;12(5):4379-4393. |
Bai MR#, Niu WB#, Zhou Y#, Gong YM, Lu YJ, Yu XX, Wei ZL, Wu W, Song HL, Yu WW, Gu BL, Cai W*, Chu X*. Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility. Aging, 2020 Apr 21;12(8):7163-7182 |
Wei-Bo Niu†, Mei-Rong Bai†, Huan-Lei Song, Yan-Jiao Lu, Wen-Jie Wu,Yi-Ming Gong, Xian-Xian Yu, Zhi-Liang Wei, Wen-Wen Yu, Bei-Lin Gu,Wei Cai* and Xun Chu*. Association study of genetic variants on PLD1, 3p24.1 and 10q11.21 regions with HSCR in the Chinese population. Frontiers in Genetics, 2020;11:738 |
Kefeng Yang#, Jie Zhu#, Jiang Wu, Yan Zhong, Xiuhua Shen, Brawnie Petrov, Wei Cai*. Maternal Vitamin D Deficiency Increases Intestinal Permeability and Programs Wnt/β‐Catenin Pathway in BALB/C Mice. JPEN J Parenter Enteral Nutr.09 April 2020 https://doi.org/10.1002/jpen.1820 |
Zhiliang Wei#, Xianxian Yu#, Wenjie Wu, Meirong Bai, Yanjiao Lu, Huanlei Song, Yiming Gong, Beilin Gu, Xun Chu*, Wei Cai*. Common variants of NRG1 and ITGB4 confer risk of Hirschsprung disease in Han Chinese population. Journal of Pediatric Surgery, 2020 Apr 21;S0022-3468(20)30268-2 |
Xian-Xian Yu#, Xun Chu#*, Wen-jie Wu, Zhi-Liang Wei, Huan-Lei Song, Mei-Rong Bai, Yan-Jiao Lu, Bei-Lin Gu, Yi-Ming Gong, Wei Cai*. Common variation of the NSD1 gene is associated with susceptibility to Hirschsprung's disease in Chinese Han population. Pediatric Research, 2020 May 7. doi: 10.1038/s41390-020-0933-3 |
Nan Wang , Jiazheng Wang, Tian Zhang, Liufang Huang, Weihui Yan, Lina Lu, Jie Jia, Yijing Tao, Wei Cai*, Ying Wang*. Alterations of gut microbiota and serum bile acids are associated with parenteral nutrition-associated liver disease. J Pediatr Surg, 2020 Jun 27;S0022-3468(20)30463-2. |
Wang Y*#, Jiang Q#, Chakravarti A, Hao Cai, Ze Xu,Wenjie Wu, Beilin Gu,Long Li*, Wei Cai*. MicroRNA-4516-mediated regulation of MAPK10 relies on 3'UTR cis-acting variants and contributes to the altered risk of Hirschsprung disease. Journal of Medical Genetics, 2020;57:634–642 |
Zhiliang Wei#, Lina Lu#, Youjie Zheng, Weihui Yan, Yijing Tao, Yongtao Xiao, Wei Cai*, Ying Wang*. Variants in the Enteric Smooth Muscle Actin γ-2 Cause Pediatric Intestinal Pseudo-obstruction in Chinese Patients. Journal of Pediatric Gastroenterology & Nutrition, 2020 Aug 17.doi: 10.1097/MPG.0000000000002897 |
Nan Wang# ,Weihui Yan#, Li Hong, Lina Lu,Yi Feng, Jiang Wu, Yijing Tao, Huijuan Ruan,Qingya Tang, Wei Cai, and Ying Wang*. Risk factors of parenteral nutrition-associated cholestasis in very-low-birthweight infants. Journal of Paediatrics and Child Health, 2020 Feb 26. doi: 10.1111/jpc.14826 |
Ying Wang#, Shanshan Chen#, Weihui Yan, Lina Lu, Yijing Tao, Yongtao Xiao*, Wei Cai*. Congenital Short-Bowel Syndrome: Clinical and Genetic Presentation in China. J Parenter Enteral Nutr, 2020 DOI: 10.1002/jpen.1974 |
Zhang T, Yan JK, Wang N, Dai LN, Wang Y, Cai W*. Autophagy may protect against parenteral nutrition-associated liver disease by suppressing endoplasmic reticulum stress. Journal of Parenteral and Enteral Nutrition, 2019 Jan;43(1):96-106 |
Yan JK, Zhang T, Dai LN, Gu BL, Zhu J, Yan WH, Cai W*, Wang Y*. CELF1/p53 axis: a sustained anti-proliferative signal leading to villus atrophy under total parenteral nutrition. FASEB Journal, 2019 Mar;33(3):3378-3391. |
Li-Na Dai, Jun-Kai Yan, Tian Zhang, Wei Cai*, Wei-Hui Yan*. Butyrate promotes the adaptation of intestinal smooth muscle cells through the yes-associated protein (YAP) pathway in a rat model of short bowel syndrome. American Journal of Translational Research,2019;11(1):453-462 |
Yongtao Xiao#*, Ying Lu, Ying Wang, Weihui Yan and Wei Cai*. Deficiency in intestinal epithelial Reg4 ameliorates intestinal inflammation and alters the colonic bacterial composition. Mucosal Immunology, 2019 Jul;12(4):919-929 |
Xiao Y, Liu R, Li X, Gurley EC, Hylemon PB, Lu Y, Zhou H*, Cai W*. Long non-coding RNA H19 contributes to cholangiocyte proliferation and cholestatic liver fibrosis in biliary atresia. Hepatology, 2019 Nov;70(5):1658-1673 |
Cui X, Wang B, Wu Y, Xie L, Xun P, Tang Q, Cai W*, Shen X*. Vegetarians have a lower fasting insulin level and higher insulin sensitivity than matched omnivores: A cross-sectional study. Nutrition Metabolism and Cardiovascular Diseases, 2019 May;29(5):467-473. |
Cao Y, Xiao Y, Zhou K, Yan J, Wang P, Yan W, Cai W*. FXR agonist GW4064 improves the liver and intestinal pathology and alters bile acid metabolism in rats undergoing small intestinal resection. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2019 Aug 1;317(2):G108-G115. |
Tian Zhang; Ying Wang; Weihui Yan; Lina Lu; Yijing Tao;Jie Jia; Wei Cai*. Microbial alteration of small bowel stoma effluents and colonic feces in infants with short bowel syndrome. Journal of Pediatric Surgery, 2019 Aug 22. pii: S0022-3468(19)30511-1. doi: 10.1016/j.jpedsurg.2019.08.004. [Epub ahead of print] |
Shen X, Tang W, Yu Z, Cai W*. The history and development of registered dietitian accreditation systems in China and other comparable countries. Nutrition Research. 2019 Oct;70:11-17 |
Qian Jiang, Yang Wang, Qi Li, Zhen Zhang, Ping Xiao, Hui Wang, Na Liu, Jian Wu, Feng Zhang, Aravinda Chakravarti, Wei Cai*, Long Li*. Sequence characterization of RET in 117 Chinese Hirschsprung disease families identifies a large burden of de novo and parental mosaic mutations. Orphanet Journal of Rare Diseases, 2019,14:237 |
Zhang D, Wen J, Zhou J, Cai W, Qian L*. Milk Fat Globule Membrane Ameliorates Necrotizing Enterocolitis in Neonatal Rats and Suppresses LipopolysaccharideInduced Inflammatory Response in IEC 6 Enterocytes. Journal of Parenteral and Enteral Nutrition, 2019 Sep;43(7):863-873. |
Ying Li ,Jiang Wu*, Yang Niu, Honghao Chen MD, Yan Zhong, Tim T. Lambers, Wei Cai. Milk Fat Globule Membrane Inhibits NLRP3 Inflammasome Activation and Enhances Intestinal Barrier Function in a Rat Model of Short Bowel. Journal of Parenteral and Enteral Nutrition, 2019 Jul;43(5):677-685 |
Lu W, Zhang X, Wu J, Mao X, Shen X, Chen Q, Zhang J, Huang L, Tang Q*. Association between trimester-specific gestational weight gain and childhood obesity at 5 years of age: results from Shanghai obesity cohort. BMC Pediatr. 2019 May 2;19(1):139 |
Lu LN, Mao XM,Sheng JY, Huang JH,Wang Y, Tang QY,Cai W*,Development and validation of a pediatric nutritional screening score (PNSS) for hospitalized children,Asia Pacific Journal of Clinical Nutrition,2018;27(1):65-71 |
Dai LN, Yan JK, Xiao YT, Wen J, Zhang T, Zhou KJ, Wang Y , Cai W*, Butyrate stimulates the growth of human intestinal smooth muscle cells by activation of yes-associated protein,Journal of Cellular Physiology, 2018;233(4):3119-3128 |
Zhang T, Wang N, Yan WH, Lu LN, Tao YJ, Li F, Wang Y*, Cai W*. Effect of a fish oil-based lipid emulsion on intestinal failure-associated liver disease in children. European Journal of Clinical Nutrition, 2018;72(10):1364-1372 |
Xiao YT, Zhou Y, Lu Ying, Zhou KJ, Cai Wei*. PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver. Cell Death & Disease, 2018;9:160 |
Yan JK, Zhu J, Gong ZZ, Wen J, Xiao YT, Zhang T, Cai W*. Supplementary choline attenuates olive oil lipid emulsion-induced enterocyte apoptosis through suppression of CELF1/AIF pathway. Journal of Cellular and Molecular Medicine, 2018;22(3):1562-1573 |
Wang Y, Yan WH, Wang J, Zhou Y, Chen J, Gu BL, Cai W*. Common genetic variants in GAL, GAP43 and NRSN1 and interaction networks confer susceptibility to Hirschsprung disease. Journal of Cellular and Molecular Medicine, 2018;22:3377-87 |
Zhao SN, Gong ZZ, Du XX, Tian CY, Wang LY, Zhou JF, Xu CF, Chen YW, Cai W*, Wu J*. Deoxycholic acid-mediated sphingosine-1-phosphate receptor 2 signaling exacerbates DSS-induced colitis through promoting cathepsin B release. Journal of Immunology Research, 2018:2481418 |
Wu S, Qian LX, Huang L, Sun XM, Su HY, Deepanjali D. Gurav, Jiang MW, Cai W*, Qian K*. A plasmonic mass spectrometry approach for detection of small nutrients and toxins. Nano-Micro Letters, 2018;10:52 |
Cai W, Phillip C.Calder, Maria F. Cury-Boaventura, Elisabeth De Waele, Julie Jakubowski, Gary Zaloga. Biological and clinical aspects of an oliveoil-based lipid emulsion-a review. Nutrients, 2018;10,776. |
Yan JK, Yan WH*, Cai W*. Fish oil-derived lipid emulsion induces RIP1-dependent and caspase 8-licensed necroptosis in IEC-6 cells through overproduction of reactive oxygen species. Lipids in Health and Disease, 2018;17(1):148-157. |
Mihatsch WA, Braegger C, Bronsky J, Cai W et al. ESPGHAN/ESPEN/ESPR guidelines on pediatric parenteral nutrition:Complications. Clinical Nutrition,2018 Dec;37(6 Pt B):2303-2305 |
Wu J, Yang KF, Wu WJ, Tang QY, Zhong Y, Gabriele Gross, Tim T. Lambers, Eric A.F.van Tol, Cai W*. Soluble Mediators From Lactobacillus rhamnosus Gorbach-Goldin Support Intestinal Barrier Function in Rats After Massive Small-Bowel Resection. Journal of Parenteral and Enteral Nutrition, 2018;42(6):1026-1034 |
Wu J, Zhong Y, Shen XH, Yang KF*, Cai W*. Maternal and early-life vitamin D deficiency enhances allergic reaction in an ovalbumin-sensitized BALB/c mouse model. Food & Nutrition Research. 2018;62:1401.doi: 10.29219/fnr.v62.1401. |
Lu W, Xiao YT, Huang JH, Lu LN, Tao YQ, Yan WH, Cao Y, Cai W*. Causes and prognosis of chronic intestinal pseudo-obstruction in 48 subjects. Medicine, 2018;97(36):e12150 |
Gong ZZ, Zhao SN, Zhou JF, Yan JK, Wang LY, Du XX, Li H, Chen YW, Cai W*, Wu J*. Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production. Molecular Immunology, 2018;104:11-19 |
Yang Y, Zheng T, Zhou J, Song HL, Cai W*, Qian LX*.Bile salt dependent lipase promotes intestinal adaptation in rats with massive small bowel resection. Bioscience Reports, 2018 May 31;38(3). pii: BSR20180077 |
Xiao Y, Zhou Y, Zhou K, Lu Y, Yan W, Cai W* Wang Y*. Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling. Experimetal & Molecular Medicine,2018 ;50(12):155 |
Zhu J, Lu T, Chen F, Yan JK, Chen F, Zhang QS, Wang JF, Yan WH, Yu TX, Tang QY, Cai W*. Choline protects against intestinal failure-associated liver disease in parenteral nutrition-fed immature rats. Journal of Parenteral and Enteral Nutrition, 2018 Feb;42(2):436-445 |
X. Chu, Yang M., Song Z. J., Dong Y., Li C., Shen M., Zhu Y. Q., Song H. D., Chen S. J., Chen Z. & Huang W. Fine mapping MHC associations in Graves' disease and its clinical subtypes in Han Chinese. Journal of Medical Genetics, 2018,55(10):685-692. |
Huang J, Yu Q, Wen J, Yan W, Lu L, Tao Y, Cai W, Wang Y*. Peripherally inserted central catheter-related complications in infants with intestinal failure. Asia Pac J Clin Nutr, 2018;27(6):1225-1229. |
Zhang MZ, Xun PC, He K, Cai W*. Adjuvant steroid treatment following Kasai portoenterostomy and clinical outcomes of biliary atresia patients: an updated meta-analysis. World Journal of Pediatrics, 2017;13 (1):20-6 |
Wen J, Yu Q, Chen HY, Chen NN, Huang SR, Cai W*. Peripherally inserted central venous catheter-associated complications exert negative effects on body weight gain in neonatal intensive care units. Asia Pacific Journal of Clinical Nutrition, 2017;26(1):1-5 |
Wang PL, Wang J, Zhou Y, Zhou KJ, Wen J, Cai W*. Expression of programmed death-1 and its ligands in the liver of biliary atresia. World Journal of Pediatrics, 2017;13(6):604-610 |
Yan JK, Zhou KJ, Huang JH, Wu QQ, Zhang T, Wang CC, Cai W*. Urinary glutamine/glutamate ratio as a potential biomarker of pediatric chronic intestinal pseudo-obstruction. Orphanet Journal of Rare Diseases, 2017;12(1):62 |
Yan WH, Hong L, Wang Y, Feng Y, Lu LN, Tao YJ, Wu J, Ruan HJ, Tang QY, Cai W*. Retrospective dual-center study of parenteral nutrition–associated cholestasis in premature neonates: 15 years’ experience. Nutrition in Clinical Practice, 2017;32(3):407-13 |
Xiao YT, Wang J, Yan WH, Zhou KJ, Cao Y, Cai W*. p38αMAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure. Cell Death & Disease, 2017;8(10):e3110 |
Yan JK, Gong ZZ, Zhang T, Cai W*. Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells. Biochemical and Biophysical Research Communications, 2017;482(4):791-795 |
Wang PL, Wang Y, Lu LN, Yan WH, Tao YJ, Zhou KJ, Jia J, Cai W*.Alterations in intestinal microbiota relate to intestinal failure-associated liver disease and central line infections. Journal of Pediatric Surgery, 2017;52(8):1318-1326 |
Cheng SY, Wang J, Pan WH, Yan WB, Shi J, Guan WB, Wang Y, Cai W*. Pathologically assessed grade of Hirschsprung-associated enterocolitis in resected colon in children with Hirschsprung's disease predicts postoperative bowel function. Journal of Pediatric Surgery,2017;52(11):1776-1781 |
Wu J, Xun PC, Tang QY, Cai W*, He K*. Circulating magnesium levels and incidence of coronary heart diseases,hypertension, and type 2 diabetes mellitus:a meta-analysis of prospective cohort studies. Nutrition Journal, 2017;16(1):60 |
Lu LP, Wan YP, Xun PC, Zhou KJ, Chen C, Cheng SY, Zhang MZ, Wu CH, Lin WW, Jiang Y, Feng HX, Wang JL, He K, Cai W*.Serum bile acid level and fatty acid composition in Chinese children with non-alcoholic fatty liver disease. Journal of Digestive Diseases,2017;18(8):461-471 |
Wang Y , Veremeyko T, Wong AH, El Fatimy R, Wei Z, Cai W, Krichevsky AM*. Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease. Neurobiology of Aging, 2017;51:156-66 |
Feng HX, Xun PC, Pike K, Wills AK, Chawes BL, Bisgaard H, Cai W, Wan YP*, He K*. In utero exposure to 25(OH) D and risk of childhood asthma,wheeze and respiratory tract infection: a meta-analysis of birth cohort studies. Journal of Allergy and Clinical Immunology, 2017;139(5):1508-17 |
Wang J, Zhang MZ, Pan WH, Wu WJ, Yan WB, Cai W*. Management of recurrent tracheoesophageal fistula after esophageal atresia and follow-up. Diseases of the Esophagus, 2017;30(9):1-8 |
Cao Y, Yan WH, Lu LN, Tao YJ, Lu W, Chen YW, Tang QY, Cai W*. Parenteral nutrition combined with rice soup can be a safe and effective intervention for congenital chylous ascites. Asia Pacific Journal of Clinical Nutrition, 2016;25(3):631-5. |
Lu LP, Xun PC, Wan YP, He K*, Cai W*. Long-term association between dairy consumption and risk of childhood obesity: a systematic review and meta-analysis of prospective cohort studies. European Journal of Clinical Nutrition. 2016;70(4):414-23. |
Lu W, Xiao YT, Huang JH, Tao YJ, Yan WH, Lu LN, Cao Y, Cai W*. Mutation in actin gamma-2 responsible for megacystis microcolon intestinal hypoperistalsis syndrome in 4 Chinese patients. Journal of Pediatric Gastroenterology and Nutrition, 2016;63(6):624-6. |
Qian LX, Song HL, Cai W*. Determination of Bifidobacterium and Lactobacillus in breast milk of healthy women by digital PCR. Beneficial Microbes, 2016;7(4):559-69. |
Wang PL, Xun PC, He K*, Cai W*. Comparison of liver transplantation outcomes in biliary atresia patients with and without prior portoenterostomy: a meta-analysis. Digestive and Liver Disease, 2016;48(4):347-52. |
Wang Y, Feng Y, Lu LN, Wang WP, He ZJ, Xie LJ, Hong L, Tang QY, Cai W*. The effects of different lipid emulsions on the lipid profile, fatty acid composition, and antioxidant capacity of preterm infants: A double-blind, randomized clinical trial. Clinical Nutrition, 2016;35(5):1023-31. |
Wang Y, Zhou KJ, Tang QY, Hong L, Feng Y, Lu LN, Wang WP, Cai W*. Effect of an olive oil-based lipid emulsion compared with a soybean oil-based lipid emulsion on liver chemistry and bile acid composition in preterm infants receiving parenteral nutrition: a double-blind, randomized trial. Journal of Parenteral and Enteral Nutrition, 2016;40(6):842-50. |
Xiao YT, Yan WH, Zhou KJ, Cao Y, Cai W*. Glucocorticoid treatment alters systemic bile acid homeostasis by regulating the biosynthesis and transport of bile salts. Digestive and Liver Disease, 2016;48(7):771-9. |
Xiao YT, Yan WH, Cao Y, Yan JK, Cai W*. Neutralization of IL-6 and TNF-alpha ameliorates intestinal permeability in DSS-induced colitis. Cytokine, 2016;83:189-92. |
Zhou KJ, Xie GX, Wen J, Wang J, Pan WH, Zhou Y, Xiao YT, Wang Y, Jia W*, Cai W*. Histamine is correlated with liver fibrosis in biliary atresia. Digestive and Liver Disease, 2016;48(8):921-6. |
Xiao YT, Wang J, Lu W, CaoY, Cai W*. Downregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChE. Cell Death & Disease, 2016;7(12):e2521 |
Xiao YT, Cao Y, Zhou KJ, Lu LN, Cai W*. Altered systemic bile acid homeostasis contributes to liver disease in pediatric patients with intestinal failure. Scientific Reports, 2016;6:39264 |
Zhao SN, Gong ZZ, Zhou JF, Tian CY, Gao YH, Xu CF, Chen YW*, Cai W*, Wu J*. Deoxycholic acid triggers NLRP3 inflammasome activation and aggravates DSS-induced colitis in mice. Frontiers in Immunology, 2016;7:536 |
Qian LX, Zhao AH, Zhang YN, Chen TL, Zeisel SH, Jia W*, Cai W*. Metabolomic approaches to explore chemical diversity of human breast-milk, formula milk and bovine milk. International Journal of Molecular Science, 2016, 17(12).pii:E2128 |
Zhu J, Wu Y, Guo YG, Tang QY, Lu T, Cai W, Huang HY*. Choline alleviates parenteral nutrition-associated duodenal motility disorder in infant rats. Journal of Parenteral and Enteral Nutrition, 2016;40(7):995-1005. |
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